Epilepsy Specialist Symposium: Interictal Epileptiform Activity and Its Meaning

8:30 AM-11:30 AM
Behavioral Health Providers
This symposium appraises the meaning of interictal activity. It examines whether interictal epileptiform discharges (IED) are predictive of seizures and whether IED can be used to determine the seizure onset zone or predict outcome after epilepsy surgery. It will also inform about the interaction of IED and cognition.

Learning Objectives

Following participation in this activity, participants will be able to:

  • Differentiate whether interictal EEG activity is pro or anticonvulsive
  • Recognize the value of interictal activity for localizing the seizure onset zone
  • Review the interaction between IED and cognition and attention
  • Discuss the spatial variation and distribution of interictal discharges
  • Comprehend clinical decision making based on interictal discharges
Chairs: Barbara Jobst, MD, PhD, and Greg Worrell, MD, PhD
Introduction and Case Presentation, Barbara Jobst, MD, PhD
Can Interictal Spikes Predict Seizures? 
1. Do IEDs Promote Seizures? Philippa Karoly, PhD
2. Rhythms of Interictal Epileptiform Activity, David Spencer, MD
Can IED Predict Seizure Focus or Surgical Outcome?
3. Does the Spatial Distribution or Frequency of IED Predict Seizure Onset Zone? Erin Conrad, MD
4. Should Ictal or Interictal Activity Guide Surgical Resection? Jean Gotman, PhD
5. The Latest Science About Interictal Activity: Excerpts from Poster Presentations Interictal Epileptiform Activity and Cognition?
6. Interictal Activity Impairs Cognition, Jon Kleen, MD, PhD
7. Should Patients with Frequent Interictal Discharges be Driving? Dorothee Kasteleijn-Nolst Trenite, MD, MPH
8. The Latest Science About Interictal Activity: Excerpts from Poster Presentations
What is an Interictal and Ahat is Ictal Epileptiform Activity?
The Ictal-Interictal Continuum, Susan MD
Questions and Conclusions, Gregory Worrell, MD, PhD