Investigators Workshops

Dec
05

Investigators Workshop: Bi-Directional Relationship Between Late-Onset Epilepsy and Alzheimer’s Disease

9:00 AM-10:30 AM
APPs
Clinicians
Fellows/Trainees

Moderators: Emily Johnson, MD and Alice D. Lam, MD, PhD

Speakers: Emily Johnson, MD; Rani Sarkis, MD, MSc; and Mouhsin Shafi, MD, PhD

Learning Objectives

Following participation in this activity, participants will be able to:

  • Describe the epidemiologic relationships between epilepsy and Alzheimer's disease
  • Evaluate the evidence for the contributions of seizures, interictal activity, and medications for cognitive decline in Alzheimer's disease
  • Discuss the pros and cons of aggressive medical treatment of seizures in patients with cognitive impairment and epilepsy

This workshop reviews the clinical and mechanistic overlap between late-onset epilepsy and Alzheimer's disease.

Current studies have demonstrated an increasing overlap between late-onset epilepsy and Alzheimer’s disease. This workshop offers participants the opportunity to discuss and evaluate the evidence in the treatment of seizures among patients with epilepsy. Speakers intend to focus on neurophysiologic studies in animal models and humans, and across multiple modalities, to derive new insights and discuss knowledge gaps and important directions for future high-impact research at the boundary between epilepsy and Alzheimer's disease.

This workshop covers:

  1. Recent population-based evidence of this important interaction between late-onset epilepsy and Alzheimer’s disease
  2. Evidence for the contributions of seizures, interictal activity, and medications for cognitive decline in Alzheimer's Disease
  3. The pros and cons of aggressive medical treatment of seizures in patients with cognitive impairment and epilepsy