Download the program book -- last updated 10/31
People with epilepsy report that the unpredictable nature of seizures is one of epilepsy’s most disabling features. Despite the perception that seizures are unpredictable, studies have demonstrated that seizures are often associated with predictors in at least 4 categories: trigger factors (measurable precipitants or exposures); premonitory features (symptoms preceding the seizure); self-prediction (the ability of some individuals to accurately predict an impending seizure); and electrographic events on intracranial EEG. Successful seizure forecasting would offer the possibility of immediate treatment to preempt the seizure, and provide an opportunity for a patient to take precautionary measures
Basic Science Skills Workshop | Tissue Clearing for the 3D Histological Visualization and Characterization of Brain Tissue
This workshop will begin with a discussion on the current limitations of histology in the context of studying brain tissue. This will be followed by an introduction to all of the current tissue clearing techniques and their respective advantages and disadvantages. Specific use cases will be described for when one tissue-clearing technique should be used over another. This conversation will then discuss many of the practical considerations of tissue clearing such as tissue size, antibody penetration, and label compatibility. This will lead into a discussion on the optical considerations for imaging
Basic Science Skills Workshop | Viral Approaches for Anatomical Tracing and Functional Connectivity in Epilepsy Circuits
Viral vector approaches are extremely useful for studying anatomical and functional connectivity, including in epilepsy circuits. This workshop will cover the basics of different types of viral vectors, where to get them, and how to use them, including pros, cons, experimental considerations, and some troubleshooting strategies. We will highlight a variety of uses of viral vectors in epilepsy research, from addressing basic anatomical questions to circuit-busting with optogenetics.
This session is intended to highlight a current controversy commonly encountered by caregivers in the neonatal intensive care unit—the timing of antiseizure medication discontinuation following acute symptomatic neonatal seizures. While many centers are trending toward earlier discontinuation of antiseizure medications in this fragile population, there is no clear expert consensus or widely accepted recommendations guiding these practices. Additionally, despite these trends, multicenter studies have demonstrated that a wide range of variability in practice still exists across US and international centers. In this SIG, while navigating a clinically relevant case, a panel
In this session, we will discuss the evolution of the concept of stigma in epilepsy through different cultures. We will describe how stigma affects people with epilepsy independent of age, setting or seizure severity. Also the impact of societal views on the stigma for patients with epilepsy. Dr. Tayeb will discuss the role of supernatural perceptions about epilepsy in the Middle Eastern cultures and its impact on stigma. Dr. Pestana-Knight will discuss the role of stigma in children and adolescents, as well as the perception of epilepsy in African-American culture