Download the program book -- last updated 10/31
This symposium focuses on the neuroanatomical, electrophysiological, and epigenetic substrates of distinct types of memory function. Memory deficits are a common comorbidity in epilepsy, and patients undergoing brain resection for control of pharmacoresistant focal seizures may experience postoperative memory decline. This session will provide the learner with an overview of current knowledge of memory structure and function, an understanding of functional reorganization of memory circuits in epilepsy, and predictors of memory outcomes after surgery.
Diagnosing and treating intractable epilepsy can be challenging. Significant progress has been made in the management of focal epilepsy but unfortunately, this is not true when it comes to treating intractable generalized epilepsy. This session is intended to provide a platform for discussion of complex approach in the diagnosis of intractable generalized epilepsy from clinical features and electroencephalographic (EEG) abnormalities use in the diagnosis of generalized epilepsy to a comprehensive approach in the medical treatment of seizures and its comorbidities. Clinical cases will be presented in order to cover a
This session will discuss the resurgence in neurosteroid therapeutics in epilepsy and related brain conditions. Neurosteroids continue to attract the attention of neurological investigators because of their potent effects on synaptic and extrasynaptic GABA-A receptor function and the mounting evidence of their clinical potential. Allopregnanolone and related neurosteroids are strong sedatives, anxiolytics, and anticonvulsants. Several synthetic agents have been developed to target neuronal GABA-A receptors. There is a resurgence in neurosteroid therapeutics, and at least four lead molecules have entered advanced clinical trials for seizure disorders. An improved mechanistic understanding
Focal cortical dysplasia (FCD) is the most prevalent surgically-amenable epileptogenic lesion in pediatric and adult patients with drug-resistant epilepsy. Advances in MRI have led to substantial gain in sensitivity for detecting these lesions. In parallel, recent evidence from histology and genetics have opened new prospects in the understanding and management of this developmental malformation. This SIG will cover the most recent research in these disciplines with the aim of promoting interdisciplinary discussion in view of an integrative FCD classification system.
NIH and Non-Profit Research Resources/Junior Investigator Workshop SIG | First Steps First: Finding Initial Research Funding and Compelling Research Aims
Early investigators may rely on funding from a variety of sources, including federal and non-profit funding. This session will give a brief overview of current mechanisms intended to financially support neurology researchers during the early stages of their career (i.e., Epilepsy Foundation, CURE, AAN fellowships, and NIH/NINDS K and F awards). Presenters will include members of each institution/foundation as well as prior and current grant recipients for panel discussion. Following the funding overview section, reviewers from NIH-NINDS study sections will provide insights into successful grant-writing for junior investigators with a