Challenges arise to providing comprehensive care for persons with intractable epilepsy, particularly in quality of life, epilepsy diets, use of CBD, surgical options, and psychosocial/mental health and neurocognitive functioning. This symposium will provide general knowledge on care for patients with intractable epilepsy in the above domains and practical solutions for addressing challenges in these domains relevant to providing comprehensive epilepsy care. Mixed didactic with case-based presentations followed by questions and answer format with the speaker panel. Concrete examples of an interprofessional approach to caring for patients with intractable epilepsy will
Three concurrent sessions highlighting selected key scientific abstracts consisting of author presentations followed by Q&A.
|Platform A: Basic Mechanisms of Epilepsy (Rooms 318-320)|
|Platform B: Neuroimaging (Room 322)|
|Platform C: Advances in Neurophysiology (Room 325)|
Investigators Workshop: Neurostimulation and Neuroimaging of Subcortical Arousal Circuits in Epilepsy
This workshop will address new exciting data and techniques for imaging networks and uncovering mechanisms of therapeutic modulation by subcortical stimulation devices in epilepsy. We will provide a comprehensive update of the neuroscience of arousal and consciousness as a general field, and as applied to epileptic seizure networks, in the context of other altered states such as anesthesia, coma or sleep. Promising findings using high field opto-fMRI and multi-site stimulation in animal models allow unprecedented visualization of cortical and limbic network changes with subcortical stimulation - with ability to modulate
This workshop will address emerging microelectrode array (MEA) technologies and their applications. Transparent electrode arrays are of interest to many researchers who work on in vivo neuronal imaging and optogenetic stimulation. In addition, in late 2018, the novel, extremely high density silicon electrode array, “Neuropixels”, became available to the general research community. Emerging innovations are not limited to the forefront of in vivo electrophysiology. Advanced materials and increased computational capability have pushed the limit of conventional MEA concepts also into in vitro assay systems. Discussion will focus on how these
Investigators Workshop: Seizures in Seniors: How Do We Identify New and Innovative Therapies for this Growing Patient Demographic?
This workshop will address the specific therapeutic needs of the fastest growing patient demographic with epilepsy diagnosis: the elderly. Despite the greater incidence of epilepsy in the elderly, as well as the overlapping pathology and increased risk of seizures in patients with Alzheimer’s disease, aged animal models are infrequently used to support antiseizure drug development. This workshop will discuss the pros and cons associated with the identification of therapeutic targets, innovation of preclinical models of aging-related seizures, and the application of comprehensive clinical pharmacology to improve therapeutic management and outcomes